Main Publications

The human thymus perivascular space is a functional niche for viral-specific plasma cells. Sarah Nuñez, Carolina Moore, Baoshan Gao, Kortney Rogers, Yessia Hidalgo,
Pedro J. del Nido, Susan Restaino, Yoshifumi Naka, Govind Bhagat, Joren C. Madsen, María Rosa Bono, Emmanuel Zorn. Sci Immunol, 2016, 1, eaah4447.

Retinoic Acid as a Modulator of T Cell Immunity. Maria Rosa Bono, Gabriela Tejon, Felipe Flores-Santibañez, Dominique Fernandez, Mario Rosemblatt, Daniela Sauma. Nutrients, 2016, 13;8(6). pii: E349. doi: 10.3390/nu8060349.

Purinergic Signaling as a Regulator of Th17 cell Plasticity. Dominique Fernández, Felipe Flores-Santibáñez, Jocelyn Neira, Francisco Osorio-Barrios, Gabriela Tejón, Sarah Nuñez, Yessia Hidalgo, Maria Jose Fuenzalida, Daniel Meza, Gonzalo Ureta, Alvaro Lladser, Rodrigo Pacheco, Claudio Acuña-Castillo, Victoria Guixé, Francisco J. Quintana, Maria Rosa Bono, Mario Rosemblatt, Daniela Sauma. Plos One, 2016, 20;11(6):e0157889. doi: 10.1371/journal.pone.0157889.

Alloreactive Regulatory T cells Allow the generation of Mixed Chimerism and Transplant Tolerance. Ruiz P, Maldondado P, Hidalgo Y, Sauma D, Rosemblatt M, and Bono MR. Front Immunol, 2015. 6: 596.

CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells. Felipe Flores-Santibáñez, Dominique Fernández, Daniel Meza, Gabriela Tejón, Leonardo Vargas, Lorena Varela-Nallar, Sebastián Arredondo, Victoria Guixé, Mario Rosemblatt, María Rosa Bono, Daniela Sauma. Immunology 2015, 146(4):582-94.

CD73 and CD39 ectonucleotidases in T cell differentiation: beyond immunosuppression. María Rosa Bono, Dominique Fernández, Felipe Flores-Santibáñez, Mario Rosemblatt, Daniela Sauma. FEBS Letters. 2015, 589 (22): 3454-60.

Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection. Moore C, Tejon G, Fuentes C, Hidalgo Y, Bono MR, Maldonado P, Fernandez R, Wood KJ, Fierro JA, Rosemblatt M, Sauma D, Bushell A. Eur J Immunol. 2015 Feb;45(2):452-63. doi: 10.1002/eji.201444743. Epub 2014 Dec 2.

T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour. Nuñez S, Saez JJ, Fernandez D, Flores-Santibañez F, Alvarez K, Tejon G, Ruiz P, Maldonado P, Hidalgo Y, Manriquez V, Bono MR, Rosemblatt M, Sauma D. Immunology. 2013 May; 139(1):61-71. doi:10.1111/imm.12055.

Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus. Jørgensen TN, Alfaro J, Enriquez HL, Jiang C, Loo WM, Atencio S, Bupp MR, Mailloux CM, Metzger T, Flannery S, Rozzo SJ, Kotzin BL, Rosemblatt M, Bono MR, Erickson LD. J Immunol. 2010 Jan 15;184(2):775-86. doi: 10.4049/jimmunol.0901322. Epub 2009 Dec 16.

Gap junctions at the dendritic cell-T cell interface are key elements for antigen-dependent T cell activation. Elgueta R, Tobar JA, Shoji KF, De Calisto J, Kalergis AM, Bono MR, Rosemblatt M, Sáez JC. J Immunol. 2009 Jul 1;183(1):277-84. doi: 10.4049/jimmunol.0801854.

Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Faure-André G, Vargas P, Yuseff MI, Heuzé M, Diaz J, Lankar D, Steri V, Manry J, Hugues S, Vascotto F, Boulanger J, Raposo G, Bono MR, Rosemblatt M, Piel M, Lennon-Duménil AM. Science. 2008 Dec 12;322(5908):1705-10. doi: 10.1126/science.1159894.

Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells. Elgueta R, Sepulveda FE, Vilches F, Vargas L, Mora JR, Bono MR, Rosemblatt M. J Immunol. 2008 May 15;180(10):6501-7.

All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. Benson MJ, Pino-Lagos K, Rosemblatt M, Noelle RJ. J Exp Med. 2007 Aug 6;204(8):1765-74. Epub 2007 Jul 9.

The essential role of chemokines in the selective regulation of lymphocyte homing. Bono MR, Elgueta R, Sauma D, Pino K, Osorio F, Michea P, Fierro A, Rosemblatt M. Cytokine Growth Factor Rev. 2007 Feb-Apr;18(1-2):33-43. Epub 2007 Feb 26.

Interleukin-4 selectively inhibits interleukin-2 secretion by lipopolysaccharide-activated dendritic cells. Sauma D, Michea P, Lennon-Duménil AM, Fierro A, Morales J, Rosemblatt M, Bono MR. Scand J Immunol. 2004 Feb;59(2):183-9.

Selective imprinting of gut-homing T cells by Peyer’s patch dendritic cells. Mora JR, Bono MR, Manjunath N, Weninger W, Cavanagh LL, Rosemblatt M, Von Andrian UH. Nature. 2003 Jul 3;424(6944):88-93.

Human chromosome 16 encodes a factor involved in induction of class II major histocompatibility antigens by interferon gamma. Bono MR, Alcaïde-Loridan C, Couillin P, Letouzé B, Grisard MC, Jouin H, Fellous M. Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6077-81.

Immunological and biochemical properties of transverse tubule membranes isolated from rabbit skeletal muscle. Rosemblatt M, Hidalgo C, Vergara C, Ikemoto N. J Biol Chem. 1981 Aug 10;256(15):8140-8.